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Wednesday, October 7, 2026The Morning Brief →Sign in
IDNAISharesINDEX

iShares Genomics Immunology and Healthcare ETF

$40.87-4.33% vs prior close
244352-WK

Price through Oct 6, 2026 · Flows through Oct 6, 2026. Figures use the latest available records, not a live quote. Fund details retrieved Oct 6, 2026. Holdings snapshot retrieved Oct 6, 2026.

The fund generally will invest at least 80% of its assets in the component securities of the index and in investments that have economic characteristics that are substantially identical to the component securities of the index and may invest up to 20% of its assets in certain futures, options and swap contracts, cash and cash equivalents. The index is composed of developed and emerging market companies that could benefit from the long-term growth and innovation in genomics, immunology and bioengineering. It is non-diversified.

Price & daily flows
38.733.428.040.87DAILY NET FLOWOct 6Feb 4Jun 4Oct 6

SOURCE: MARKET TAPE & DAILY CREATION/REDEMPTION RECORDS · 1Y SHOWN · NET +$106M OVER THIS RANGE

The desk’s read

Money keeps arriving — +$49M of net inflows over the past month, about 15.4% of the fund's asset base, while the price has returned +56.1% so far this year. At 0.47% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$317Massets under management
0.47%expense ratio · $47 per $10,000 a year
+$49Mnet flow, trailing month
195Kavg daily volume, 30 days
63holdings · US-domiciled
2019listed June 11, 2019 · beta 0.98
The book at a glance
MRNA-7.8%TWST-18.6%GSK+0.1%IOVA-8.4%RVMD-3.8%MRK+1.7%REGN+1.7%IBRX-6.6%VRTX-0.2%EXEL-0.9%INCY-1.2%BNTX-2.0%CAI-9.7%ABCL-4.6%IDYA-3.8%ROP-0.3%RCUS-1.9%NVAX-9.9%CRSP-5.8%VIR-1.5%NUVB-1.4%PSNL-2.3%SAN+0.8%GMAB-1.8%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

HoldingsDownload CSV
#HoldingWeightPriceDay52-wk
1MRNAMODERNA11.83%$187.46-7.8%
2TWSTTWIST BIOSCIENCE8.18%$166.97-18.6%
3GSKGSK2.48%$46.60+0.1%
4IOVAIOVANCE BIOTHERAPEUTICS4.76%$12.96-8.4%
5RVMDREVOLUTION MEDICINES3.84%$199.87-3.8%
6MRKMERCK & CO3.19%$141.94+1.7%
7REGNREGENERON PHARMACEUTICALS3.16%$738.72+1.7%
8IBRXIMMUNITYBIO3.39%$9.69-6.6%
9VRTXVERTEX PHARMACEUTICALS3.11%$502.31-0.2%
10EXELEXELIXIS3.09%$58.33-0.9%
11INCYINCYTE3.08%$112.73-1.2%
12BNTXBIONTECH SE3.06%$95.73-2.0%
13CAICaris Life Sciences3.23%$27.45-9.7%
14ABCLABCELLERA BIOLOGICS2.80%$13.15-4.6%
15IDYAIDEAYA BIOSCIENCES2.74%$36.63-3.8%

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Sector weights
Health Care99.7%
Cash and/or Derivatives0.33%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Country weights
United States69%
Germany6.32%
France5.2%
Japan4.68%
Denmark3.99%
Switzerland2.82%
Canada2.8%
United Kingdom2.54%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Performance
1 week-3.4%
1 month+2.8%
3 months+17.8%
6 months+39.7%
YTD+56.1%
1 year+66.5%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week+$43M
1 month+$49M
3 months+$80M
YTD+$106M
1 year+$106M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows
OctNovDecJanFebMarAprMayJulAugSepOct
DAILY CREATION/REDEMPTION RECORDS, TRAILING TWELVE MONTHS
The risk read
31%realized volatility, 30 days (annualized)
29%realized volatility, 1 year
-10.7%deepest fall from a peak, 1 year
-4.3%latest close versus that peak

The top holding is 11.8% of the book; the top ten carry 49%. Spread across 53+ names, it behaves like roughly 24 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
9calls · latest snapshot
6puts · latest snapshot
0.67put/call ratio
191Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$52M$54M
TWST TWIST BIOSCIENCE$8M$10M
GMAB GENMAB A$5M$1M
MRK MERCK & CO$3M$2M
IOVA IOVANCE BIOTHERAPEUTICS$2M$2M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against IDNA

Due diligence cuts both ways. These funds sit on the same shelf and beat IDNA on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW State Street SPDR Portfolio Developed World ex-US ETF0.03%$41B+$286M-44bp on fee · 129× the assets · +$286M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-44bp on fee · 58× the assets · +$199M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.4B+$497M-43bp on fee · 102× the assets · +$497M in over the monthHead-to-head
IGSB iShares 1-5 Year Investment Grade Corporate Bond ETF0.04%$23.3B+$575M-43bp on fee · 73× the assets · +$575M in over the monthHead-to-head
IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF0.04%$18.6B+$412M-43bp on fee · 59× the assets · +$412M in over the monthHead-to-head
Sign in to save this to The RecordA timestamped copy for the file — documentation, not advice.
InstrumentsHarvest substitutesTrade cost at $1MClient tearsheetStress this fund
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